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有机磷中毒的机制

时间：2022-12-01

有机磷一般指敌畏、乐果等，有机磷酯磷原子具有亲电子性，与AChE酯解部位丝氨酸羟基上的亲核氧原子与共价键结合形成磷酰化AChE，磷酰化酶不能自行水解AChE失去活动，造成ACh大量积聚在体内，引起一系列中毒症状。

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[ DB ] INIT mysql
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